منابع مشابه
Characterization of a pneumococcal meningitis mouse model
BACKGROUND S. pneumoniae is the most common causative agent of meningitis, and is associated with high morbidity and mortality. We aimed to develop an integrated and representative pneumococcal meningitis mouse model resembling the human situation. METHODS Adult mice (C57BL/6) were inoculated in the cisterna magna with increasing doses of S. pneumoniae serotype 3 colony forming units (CFU; n ...
متن کاملacute disseminated encephalomyelitis following pneumococcal meningitis infection
introduction acute disseminated encephalomyelitis (adem) is an acute inflammatory and demyelinating disease of the central nervous system, resulting in various neurological symptoms. usually, the disease appears following vaccination or systemic viral infections. in rare cases, the disease appears following pneumococcal infections. case presentation the patient was a 27 year-old man who was ref...
متن کاملPneumococcal meningitis: development of a new animal model.
HYPOTHESIS The rat is a suitable animal to establish a model for the study of pneumococcal meningitis postcochlear implantation. BACKGROUND There has been an increase in the number of cases of cochlear implant-related meningitis. The most common organism identified was Streptococcus pneumoniae. Whether cochlear implantation increases the risk of pneumococcal meningitis in healthy subjects wit...
متن کاملPneumococcal meningitis: current pathophysiologic concepts.
nervous system.31 It is rapidly fatal if not treated early and effectively with antibiotics that achieve bactericidal activity at the site of infection, which is in the subarachnoid space filled with cerebrospinal fluid (CSF).28 For the last 40-50 years, the /3-lactam antibiotics have fulfilled this function. However, with the emergence of resistance to these and other antibiotics, the future a...
متن کاملPneumococcal meningitis in Jamaican children.
OBJECTIVE To describe the clinical features and outcome of pneumococcal meningitis in Jamaican children. METHODS All patients admitted to the Bustamante Hospital for Children, during the period 1995-1999, who had pneumococcus isolated from cerebrospinal fluid (CSF) or pleocytosis in association with a blood culture isolate of pneumococcus were selected. Demographic, clinical and laboratory da...
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ژورنال
عنوان ژورنال: Otology & Neurotology
سال: 2006
ISSN: 1531-7129
DOI: 10.1097/01.mao.0000227898.80656.54